Automatic motion correction for myocardial blood flow estimation improves diagnostic performance for coronary artery disease in

• Tác giả: Daniel S Berman, Valerie Builoff, Marcelo Di Carli, Hidesato Fujito, Cathleen Huang, Mark C Hyun, Paul Kavanagh, Keiichiro Kuronuma, Mark Lemley, Yuka Otaki, Piotr J Slomka, Serge D Van Kriekinge, Chih-Chun Wei
• Ngôn ngữ: eng
• Ký hiệu phân loại: 017.3 *+Classified auction catalogs
• Thông tin xuất bản: United States : Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology , 2025
• Bộ sưu tập: NCBI
• ID: 89519

Tóm tắt

 BACKGROUND: Motion correction (MC) is critical for accurate quantification of myocardial blood flow (MBF) and flow reserve (MFR) from METHODS: In total, 231 patients who underwent invasive coronary angiography and rest/pharmacologic stress RESULTS: Manual MC took 10 minutes per case (both stress and rest) on average, while automatic MC required <
 10 seconds. The area under the receiver operating characteristic curves (AUCs) for significant CAD using minimal segmental MBF were comparable between automatic and manual MC (AUC = 0.877 automatic, AUC = 0.888 Reader 1 and AUC = 0.892 Reader 2
  all P >
  0.05). AUCs of minimal segmental MBF with manual and automatic MC were significantly higher than without MC (P <
  0.05 for both). Similar findings were observed with minimal segmental MFR. CONCLUSIONS: Automatic MC can be performed rapidly, with diagnostic performance for predicting obstructive CAD comparable to manual MC. This method could be utilized for analysis of MBF/MFR in patients undergoing