Differential Characteristics on TCR Embedding Landscape Among Immune Checkpoint Blockade Responders Versus Non-Responders Against Non-Small Cell Lung Carcinoma.

• Tác giả: Peiling Tsou, Chang-Jiun Wu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 133.594 Types or schools of astrology originating in or associated with a
• Thông tin xuất bản: Germany : European journal of immunology , 2025
• Bộ sưu tập: NCBI
• ID: 89676

Tóm tắt

For each patient in the NSCLC cohort, TCR sequences were converted into numerical vectors using the TCR2Vec model and projected onto a 2D landscape. The aggregated fractions of anti-LAA TEGs per patient were calculated. ICB responders had over-represented anti-LAA TEGs compared to non-responders.