Photothrombolytics: A light-driven technology for the targeted lysis of thrombi.

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Tác giả: Basanta Acharya, Aadra P Bhatt, Lauren Haar, Tomohiro Kawano, David S Lawrence, Nigel Mackman, Caylie A McGlade, Rani S Sellers, Xianming Tan, Brianna M Vickerman, Haifeng Yin

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Netherlands : Journal of controlled release : official journal of the Controlled Release Society , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 89701

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Occlusive blood clots remain a significant global health challenge and result in emergencies that are main causes of death and disability worldwide. Thrombolytic agents (including tissue plasminogen activator, tPA) are the only pharmacological means to dissolve blood clots. However, these drugs have modest efficacy and severe safety concerns persist. We have developed light-responsive tPA-loaded red blood cells (tPA-RBCs

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