Pentacyclic triterpenoids with cytotoxic activity from the stems of Syzygium jambos (L.) Alston.

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Tác giả: Jieting Chen, De-An Guo, Yuepei Huang, Wei Li, Zhilong Liu, Lihua Peng, Weilin Qiao

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Netherlands : Fitoterapia , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 89815

Phytochemical investigation of the stems of Syzygium jambos (L.) Alston resulted in the isolation of five new pentacyclic triterpenoids, including three oleananes (1, 2, and 5) and two ursanes (3 and 4), along with 23 known compounds (6-28). Their structures were elucidated by comprehensive spectroscopic analysis and chemical methods. All isolated compounds were evaluated for their cytotoxic activities against two lung carcinoma cell lines, H1975 and HCC827. Among them, compounds 2, 7, 11, 13-16, 18, and 23 exhibited significant cytotoxic activities against H1975 and/or HCC827 cells, with IC
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