Pathogenic role for CD101-negative neutrophils in the type I interferon-mediated immunopathogenesis of tuberculosis.

• Tác giả: Yi Cai, Shreya Das, Elizabeth McDonough, Bibhuti B Mishra, Lokesh K Mishra, Tanvir N Nafiz, Poornima Sankar, Mohd Saqib, Selvakumar Subbian, Ximeng Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 571.939 Pathological aging and death
• Thông tin xuất bản: United States : Cell reports , 2025
• Bộ sưu tập: NCBI
• ID: 89854

Tóm tắt

Neutrophils are vital for immunity against Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), yet their heterogeneous nature suggests a complex role in TB pathogenesis. Here, we identify two distinct neutrophil populations based on CD101 expression, highlighting their divergent roles in TB. CD101-negative (CD101