SPR is a fast and straightforward method to estimate the binding constants of cyclic dinucleotides to their binding partners, such as STING or poxin.

• Tác giả: Evzen Boura, Vojtech Duchoslav, Martin Klima, Hagen Sülzen
• Ngôn ngữ: eng
• Ký hiệu phân loại: 242.3 Prayers and meditations for church year, other Christian feast and fast days
• Thông tin xuất bản: Netherlands : Biophysical chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 90685

Tóm tắt

The development of small molecule drugs that target protein binders is the central goal in medicinal chemistry. During the lead compound development process, hundreds or even thousands of compounds are synthesized, with the primary focus on their binding affinity to protein targets. Typically, IC