Outcomes and Predictors of Different Flow-Gradient Patterns of Aortic Stenosis After Transcatheter Aortic Valve Replacement.

• Tác giả: Besir Besir, Serge Harb, Odette Iskandar, Samir R Kapadia, Amar Krishnaswamy, Maryam Muhammad Ali Majeed-SAidan, Rhonda Miyasaka, Zoran Popovic, Rishi Puri, Judah Rajendran, Shivabalan Kathavarayan Ramu, Grant Reed, James Yun
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : The American journal of cardiology , 2025
• Bộ sưu tập: NCBI
• ID: 90760

Tóm tắt

 This study sought to explore the clinical factors associated with classical low-flow low-gradient (C-LFLG) and normal-flow low-gradient (NFLG) aortic stenosis (AS) compared with high-gradient (HG) AS. We also compared clinical and echocardiographic outcomes after transcatheter aortic valve replacement (TAVR) across flow-gradient patterns. Patients with C-LFLG AS have a higher mortality rate after TAVR than those with HG AS. However, what leads to C-LFLG AS and the predictors of mortality in this population remain unclear. In this retrospective, single-center study involving 1,415 patients with severe AS, patients were classified as having (1) HG AS (aortic valve mean gradient [MG] >
 40 mm Hg), (2) C-LFLG AS (MG <
 40 mm Hg, stroke volume index <
 35 ml/m