The objective of present study was to examine the potential use of pomegranate flower extracts (PFEs) obtained from water and ethanol at antimicrobial doses in nitrite-reduced chicken sausages. The impact of the extracts on the physicochemical, textural, and sensory attributes of the sausages was evaluated using both reduced doses of nitrite and a nitrite-free preparation. The results revealed that incorporating PFE resulted in a sixfold and twofold enhancement in total phenolic content and antioxidant activity, respectively. The DPPH radical scavenging activity in sausages produced with ethanol-based PFE was more than twice as high as in sausages treated with sodium nitrite. Additionally, the combination of low-dose nitrite with PFE showed a reduction in TBARS values, leading to the prevention of lipid oxidation. Sausages with PFE exhibited lower pH and redness values, while maintaining similar aroma and odor characteristics as the controls. Although there was a slight negative impact on texture, color, and overall acceptability, PFE can be considered a potential alternative for improving bioactive content and oxidative stability of low-nitrite chicken sausages. The application of PFE could offer a promising opportunity to enhance the nutritional profile and quality attributes of processed meat products.