In this study, we designed a novel and straightforward intestinal drug delivery system using porous starch (PS) and carboxymethyl cellulose (CMC). Initially, native starch (NS) was hydrolyzed into porous starch (PS) using α-amylase (AM) and amyloglucosidase (AMG), with scanning electron microscopy (SEM) confirming the successful formation of PS. The model drug quercetin (Que) was then adsorbed onto PS, achieving an adsorption efficiency of 86.48%. BET surface area analysis showed that PS had a surface area of 23.1243 m