In-situ formation of deep eutectic supramolecule based extraction method coupled to valve switching ion chromatography mass spectrometry for the determination of aminoglycosides in meat.

• Tác giả: Jianchao Deng, Xuxia Liang, Runkun Zhang, Zhixiong Zhong
• Ngôn ngữ: eng
• Ký hiệu phân loại: 636.0885 Animal husbandry
• Thông tin xuất bản: Netherlands : Journal of chromatography. A , 2025
• Bộ sưu tập: NCBI
• ID: 95672

Tóm tắt

A novel extraction methodology was developed for extracting nine aminoglycosides (AGs) from meats based on the in-situ formation of deep eutectic supramolecule between analytes and gallic acid. Good chromatographic separation was achieved on a cation-exchange column utilizing solely a diluted organic acid as the eluent. A matrix-switching system was created to divert common inorganic cations from the column effluent to waste, reducing conductance peak values by 99.8 % and mitigating ion suppression in high-resolution electrospray ionization. The methodology was validated and exhibited excellent linearity across a concentration range of 20-800 μg L