Spirocyclic compounds as innovative tools in drug discovery for medicinal chemists.

• Tác giả: Francielle D Aguiar, Luiza R Cruz, Luiz Fernando N de Oliveira, Ramon G de Oliveira, Gleiston G Dias, Luiz C Dias, João Pedro Nogueira, Marina T Varela
• Ngôn ngữ: eng
• Ký hiệu phân loại: 621.9 Tools
• Thông tin xuất bản: France : European journal of medicinal chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 96587

Tóm tắt

The occurrence of spirocyclic motifs in clinical candidates and approved drugs is on the rise. This is related to the improvement of drug-like properties that can be achieved by introducing this sp