Structural, mechanical, antioxidant and antibacterial properties of double cross-linked chitosan cryogels as hosts for thymol.

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Tác giả: Maria Valentina Dinu, Ecaterina Stela Dragan, Alina Nicolescu, Ioana Victoria Platon

Ngôn ngữ: eng

Ký hiệu phân loại: 784.1886 General principles, musical forms, instruments

Thông tin xuất bản: Netherlands : International journal of biological macromolecules , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 97547

The practical applications of essential oils (EOs) are limited by their hydrophobicity, volatility and instability. To overcome these drawbacks, the incorporation of EOs into porous materials is recommended. Chitosan (CS)-based composite cryogels as hosts for thymol as a volatile model terpenoid were developed using a double cross-linking of CS with glutaraldehyde (GA) and monochlorotriazinyl-β-cyclodextrin (MCT-β-CD), either in one-pot synthesis or through sequential cross-linking, first with GA and then with MCT-β-CD, resulting in CSCAV composites. Cross-linking with GA occurred under cryogelation conditions, while cross-linking with MCT-β-CD took place by heating at 60-80 °C. The composite cryogels were characterized by FTIR,
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