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Tìm được 77 kết quả
Dissecting Structural Requirements of Leucinostatin A Derivatives for Antiprotozoal Activity and Mammalian Toxicity
Tác giả: Lukas Rimle, Dimanthi Pliatsika, Noëlle Arnold, Sandra Kurth, Marcel Kaiser, Pascal Mäser, Michael Kemmler, Michael Adams, Rainer Riedl, Christoph von Ballmoos
Xuất bản: United States: Journal of medicinal chemistry , 2025
Bộ sưu tập: NCBI
ddc:  553.453
 
Design, Synthesis, and Mechanism Study of Novel BMX Inhibitors Based on the Core of 1,3,5-Triazin-2-Amine for the Treatm...
Tác giả: Nan Wang, Xianxia Zeng, Ting Ma, Linhong He, Mengyang Xu, Yamin Shi, Jie Zhang, Zhen Ling, Xin Xie, Tingsheng Qin, Huaizheng Huang, Jie Yang
Xuất bản: United States: Journal of medicinal chemistry , 2025
Bộ sưu tập: NCBI
ddc:  553.3
 
Target Identification with Live-Cell Photoaffinity Labeling and Mechanism of Action Elucidation of ARN23765, a Highly Po...
Tác giả: Elisa Romeo, Francesco Saccoliti, Fabio Bertozzi, Riccardo Ocello, Angela Andonaia, Caterina Allegretta, Cristina Pastorino, Nicoletta Pedemonte, Federico Falchi, Onofrio Laselva, Tiziano Bandiera
Xuất bản: United States: Journal of medicinal chemistry , 2025
Bộ sưu tập: NCBI
ddc:  204.4086
 
Opening the Door to a New Treatment Paradigm: The Re-emergence of Chymase Inhibitors
Tác giả: Franz von Nussbaum, Giambattista Testolin
Xuất bản: United States: Journal of medicinal chemistry , 2025
Bộ sưu tập: NCBI
ddc:  006.333
 
Opto-Epigenetic Regulation of Histone Arginine Asymmetric Dimethylation via Type I Protein Arginine Methyltransferase In...
Tác giả: Shuting Xu, Kaiqi Long, Tianyi Wang, Yangyang Zhu, Yunjiao Zhang, Weiping Wang
Xuất bản: United States: Journal of medicinal chemistry , 2025
Bộ sưu tập: NCBI
ddc:  001.432
 
Impact of Fluorine Pattern on Lipophilicity and Acid-Base Properties of 2-(Thiofluoroalkyl)pyridines: Insights from Expe...
Tác giả: Miguel Bernús, Gonzalo D Núñez, Will C Hartley, Marc Guasch, Jordi Mestre, Maria Besora, Jorge J Carbó, Omar Boutureira
Xuất bản: United States: Journal of medicinal chemistry , 2025
Bộ sưu tập: NCBI
ddc:  354.353
 
Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)
Tác giả: Paige J Monsen, Prashant V Bommi, Michael Egozi, Sonam Jha, Sara F Dunne, Hong Jiang, Guiqin Song, Fang Zhang, Steven Kregel, Ali Vaziri-Gohar, Sean W Fanning, Pilar Sanchez-Gomez, Arabela A Grigorescu, Jacob M Allen, Bakhtiar Yamini, Rimas V Lukas, Derek A Wainwright, Gary E Schiltz, Kristen L Lauing, Yingyu Mao, Payton Berardi, Lijie Zhai, Oluwatomilayo Ojo, Manon Penco-Campillo, Taylor Koch
Xuất bản: United States: Journal of medicinal chemistry , 2025
Bộ sưu tập: NCBI
ddc:  004.2
 
Design, Synthesis, and Characterization of GluN2A Negative Allosteric Modulators Suitable for In Vivo Exploration
Tác giả: François P Bischoff, Sven Van Brandt, Celine Schalk-Hihi, Robyn Miller, David Duda, Paul Shaffer, Scott Ballentine, Sirak Simavorian, Brian Lord, Robert A Neff, Pascal Bonaventure, Harrie J M Gijsen, Marcel Viellevoye, Michel De Cleyn, Michel Surkyn, Rodrigo J Carbajo, Maria Dominguez Blanco, Berthold Wroblowski, Nathan K Karpowich, Ruth A Steele
Xuất bản: United States: Journal of medicinal chemistry , 2025
Bộ sưu tập: NCBI
ddc:  129
 
Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists
Tác giả: Brian S Gerstenberger, Ray Unwalla, Gary M Chinigo, Andrew Flick, Neelu Kaila, Daniel Lamb, James J Mousseau, Nootaree Niljianskul, Mathieu Rappas, John I Trujillo, Michael L Vazquez, Atli Thorarensen, Kathleen A Farley, Mark E Schnute, Philippe Nuhant, Vincent M Lombardo, Wei Li, Kimberly Crouse, Richard K Frisbie, Eric P Arnold, Mark W Bundesmann
Xuất bản: United States: Journal of medicinal chemistry , 2025
Bộ sưu tập: NCBI
ddc:  021.28
 
Design, Synthesis, and Biological Evaluation of BODIPY-Caged Resiquimod as a Dual-Acting Phototherapeutic
Tác giả: Eslam Roshdy, Haruto Taniguchi, Yoki Nakamura, Haruko Takahashi, Yutaka Kikuchi, Ismail Celik, Elsayed S I Mohammed, Yasuhiro Ishihara, Norimitsu Morioka, Manabu Abe
Xuất bản: United States: Journal of medicinal chemistry , 2025
Bộ sưu tập: NCBI
ddc:  129
 
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