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Tìm được 21 kết quả
Structure-based design of new anticancer N3-Substituted quinazolin-4-ones as type I ATP-competitive inhibitors targeting the deep hydrophobic pocket of EGFR
Tác giả: Ragaa Y El-Mahdy, Noha Galal, Rahma Lotfy, Reem K Arafa
Xuất bản: United States: Computers in biology and medicine , 2025
Bộ sưu tập: NCBI
ddc:  548.8
 
Structure-based Design of Chimeric Influenza Hemagglutinins to Elicit Cross-group Immunity
Tác giả: Karla M Castro, Reyhaneh Ayardulabi, Ventzislav Vassilev, Xavier Saelens, Bruno E Correia, Sarah Wehrle, Hongrui Cui, Sandrine Georgeon, Joseph Schmidt, Shuhao Xiao, Nishat Seraj, Wayne Harshbarger, Corey P Mallett
Xuất bản: United States: bioRxiv : the preprint server for biology , 2025
Bộ sưu tập: NCBI
ddc:  378.242
 
A structure-based framework for selective inhibitor design and optimization
Tác giả: Yurong Zou, Tao Guo, Lijuan Chen, Zhiyuan Fu, Zhongning Guo, Weichen Bo, Dengjie Yan, Qiantao Wang, Jun Zeng, Dingguo Xu, Taijin Wang
Xuất bản: England: Communications biology , 2025
Bộ sưu tập: NCBI
ddc:  576.58
 
Computational structure-based design of antiviral peptides as potential protein-protein interaction inhibitors of rabies virus phosphoprotein and human LC8
Tác giả: Saman Rahmati, Fatemeh Zandi, Khadijeh Ahmadi, Ahmad Adeli, Niloofar Rastegarpanah, Massoud Amanlou, Behrouz Vaziri
Xuất bản: England: Heliyon , 2025
Bộ sưu tập: NCBI
ddc:  615.731
 
Structure-based design, synthesis and biological evaluation of a novel d-amino acid-containing peptide inhibitor by blocking the RAD51-BRCA2 interaction for the treatment of kidney cancer
Tác giả: Jianjun Wang, Lixia Guan, Jun Wang, Shengnan Yin, Junyi Gao, Yan Zhang, Miao-Miao Niu, Jindong Li, Ying Li
Xuất bản: France: European journal of medicinal chemistry , 2025
Bộ sưu tập: NCBI
ddc:  621.48332
 
Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1'-P2' ligands [electronic resource]
Tác giả:
Xuất bản: Argonne, Ill. : Oak Ridge, Tenn: Argonne National Laboratory ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy , 2017
Bộ sưu tập: Báo, Tạp chí
ddc:  610
 
Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design [electronic resource]
Tác giả:
Xuất bản: Washington, D.C. : Oak Ridge, Tenn: United States. Dept. of Energy. Office of Science ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy , 2018
Bộ sưu tập: Báo, Tạp chí
ddc:  574.8
 
Drugging an undruggable pocket on KRAS [electronic resource]
Tác giả:
Xuất bản: Bethesda, Md. : Oak Ridge, Tenn: National Institutes of Health (U.S.) ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy , 2019
Bộ sưu tập: Báo, Tạp chí
ddc:  615.7
 
Current Aspects of Radiopharmaceutical Chemistry
Tác giả: Peter Brust (Ed)
Xuất bản: Basel, Switzerland: MDPI - Multidisciplinary Digital Publishing Institute , 2018
Bộ sưu tập: Tài liệu truy cập mở
eBook (pdf)
ddc: 
 
Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease [electronic resource]
Tác giả:
Xuất bản: Washington, D.C. : Oak Ridge, Tenn: United States. Dept. of Energy. Office of Science ; Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy , 2022
Bộ sưu tập: Báo, Tạp chí
ddc:  615.91
 
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